US
Nutramax

Nutramax Denamarin for Dogs

  • Probiotic
  • 75
  • 1
  • 0 ounces
4.5/ 5 on Amazon4,600Amazon ratings1,000+bought last month4.4ProductDome score
  • Better rated than 55%
  • More reviewed than 83%
High confidenceLast refreshed Aug 4, 2026Amazon data + ProductDome analysis · methodology
Best forYour veterinarian has recommended SAMe and silybin supplementation for liver support.

A liver support supplement worth stocking when a veterinarian has actually flagged a liver concern, not something to add on a hunch.

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ProductDome scorecard

How it ranks among the 129 probiotics we track

4.4/ 5ProductDome scoreHigh confidence
Owner satisfaction · 56% of scorecategory median 4.4★4.5

4.5★ across 4,600 Amazon ratings, Bayesian-smoothed toward the category average.

Evidence strength · 17% of scorecategory median 623 ratings4.6

4,600 Amazon ratings, weighted on a log scale so huge counts don't drown everything.

Buyer demand · 11% of score4.1

1,000+ bought on Amazon last month.

Data quality · 11% of score3.8

Brand identity, imagery, description and spec coverage.

The ProductDome score is separate from the Amazon rating shown above: it combines the Bayesian-smoothed Amazon rating with evidence volume, tracked demand, and data quality across the 129 probiotics we track - how the scorecard works · full probiotics data report. Confidence: high - strong rating volume and complete data.Last refreshed Aug 4, 2026. Data-computed, not a hands-on test. Compiled by the ProductDome Research Team.

Overview

Denamarin combines SAMe (S-adenosylmethionine) at 225 mg with an 82 mg silybin-phosphatidylcholine complex in a liver flavored chewable tablet, dosed once daily and sold here in a 75 count bottle.

Nutramax positions it as liver support rather than a cure, and it's the kind of supplement typically flagged by a veterinarian after bloodwork shows elevated liver enzymes rather than picked up as general wellness insurance. Silybin, a milk thistle derived compound, is paired with SAMe for its antioxidant role.

  • Model DENAMCHW75, 75 chewable tablets
  • 225 mg SAMe plus 82 mg silybin complex per tablet
  • Liver flavored for at-home dosing
  • Made by Nutramax Laboratories Veterinary Sciences

Who it's for

Best suited to dogs under veterinary care for liver enzyme concerns, aging-related liver support, or as a companion supplement alongside medications known to stress the liver.

Strengths and trade-offs

Drawn from this product's published specifications.

What stands out
  • Liver flavored chewable, no pilling required
  • 225 mg SAMe with a silybin-phosphatidylcholine complex per tablet
  • 75 count bottle for daily dosing
What to check first
  • Targeted liver formula, not a general supplement
  • Best used under veterinary guidance rather than self-diagnosed

Performance notes

SAMe is involved in liver cell repair processes and is commonly paired with silybin for its antioxidant effect, and the chewable tablet format is built for daily at-home dosing without needing to pill the dog.

Specifications

BrandNutramax
ModelDENAMCHW75
Dimensions & fit
Item Weight0 ounces
Included components
Unit Count75
Other details
Number Of Items1
Specific Uses For Productliver function
Item FormTablet
Item Type NameLiver supplement
FlavorLiver
Product BenefitsAntioxidant
Model NumberDENAMCHW75
Upc755970631203
Manufacturer Part Number015NM-DC225
AsinB0039P4R8O
Target SpeciesDog
ManufacturerNutramax Laboratories Veterinary Sciences, Inc.
Active IngredientsS-Adenosylmethionine* 225 mg, Silybin-phosphatidylcholine complex (SPC) 82 mg. *Contains NMXSS75® S-Adenosylmethionine, proprietary veterinary researched specifications. Providing 24 mg of Silybin A+B
Best Sellers Rank#1,950 in Pet Supplies (See Top 100 in Pet Supplies) #50 in Dog Digestive Remedies
Customer Reviews{'ratings_count': '4,670', 'stars': '4.5'}

How it compares

This product against the closest alternatives we track in probiotics.

ProductAmazon ratingRatingsProductDome score
Nutramax Denamarin for DogsThis product4.5 / 54,6004.4 / 5
Pro Plan Veterinary Diets FortiFlora Chewable Probiotic Tablets for Dogs and PuppiesPurina Pro Plan4.7 / 55,0464.6 / 5
Zesty Paws Probiotics for DogsZesty4.5 / 526,1304.5 / 5
Native Pet Pumpkin for DogsNative4.5 / 59,7214.5 / 5
Nutri-Vet Pre & Probiotics for DogsNutri-Vet4.4 / 515,8174.5 / 5
Frequently asked

Questions about the Nutramax DENAMCHW75

Common buyer questions answered straight from the product spec data - no fluff, no "it depends".

What is the active ingredient in Nutramax Denamarin?

Each tablet contains 225 mg of SAMe (S-adenosylmethionine) plus an 82 mg silybin-phosphatidylcholine complex.

How many tablets are in the DENAMCHW75 bottle?

75 chewable tablets.

Is Denamarin flavored?

Yes, the tablets are liver flavored to make daily dosing easier without pilling.