US
IsisPharma

IsisPharma SG_B00CI2KP9O_US Serum

  • Serum
  • All
  • 1 fl oz
  • All
4.5/ 5 on Amazon750Amazon ratings3.8ProductDome score
  • More reviewed than 64%
High confidenceLast refreshed Aug 4, 2026Amazon data + ProductDome analysis · methodology
Best forYou want a multi-acid serum targeting uneven skin tone and texture

An acid-forward serum combining vitamin C, glycolic acid, salicylic acid and licorice, built for treating uneven pigment rather than daily gentle hydration.

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ProductDome scorecard

How it ranks among the 293 serums we track

3.8/ 5ProductDome scoreHigh confidence
Owner satisfaction · 56% of scorecategory median 4.4★4.5

4.5★ across 750 Amazon ratings, Bayesian-smoothed toward the category average.

Evidence strength · 17% of scorecategory median 398 ratings3.6

750 Amazon ratings, weighted on a log scale so huge counts don't drown everything.

Buyer demand · 11% of score0.4

Modest tracked demand last month.

Data quality · 11% of score3.8

Brand identity, imagery, description and spec coverage.

The ProductDome score is separate from the Amazon rating shown above: it combines the Bayesian-smoothed Amazon rating with evidence volume, tracked demand, and data quality across the 293 serums we track - how the scorecard works · full serums data report. Confidence: high - strong rating volume and complete data.Last refreshed Aug 4, 2026. Data-computed, not a hands-on test. Compiled by the ProductDome Research Team.

Overview

IsisPharma's serum pairs ascorbic acid, glycolic acid, licorice and salicylic acid in a 30 milliliter, aloe-scented formula aimed at exfoliating and evening out pigment, and is labeled for all skin types and tones.

The ingredient list leans toward acids: vitamin C (ascorbic acid) for brightening, glycolic and salicylic acid for exfoliation, plus licorice, a combination more associated with active treatment serums than gentle daily hydrators. Anyone new to acid exfoliants should ease in gradually given two exfoliating acids in one formula.

  • 30 milliliter multi-acid serum
  • Ascorbic acid, glycolic acid, salicylic acid and licorice
  • Targets uneven pigment
  • Aloe scented

Who it's for

Suits people specifically targeting uneven pigment and texture who are already comfortable with acid exfoliants. Not the first choice for sensitive or acid-reactive skin, since it combines two exfoliating acids alongside vitamin C in one step.

Strengths and trade-offs

Drawn from this product's published specifications.

What stands out
  • Combines vitamin C with two exfoliating acids and licorice
  • Targets uneven pigment specifically
  • Labeled for all skin types and tones
What to check first
  • Multiple active acids in one formula may be strong for sensitive or beginner skin
  • No mention of buffering ingredients to offset acid irritation

Performance notes

Glycolic and salicylic acid work as exfoliants from different angles, glycolic on the skin surface and salicylic through pores, while ascorbic acid and licorice are included for roles in brightening and evening pigment, making this a more active formula than a plain hydrating serum.

Specifications

BrandIsisPharma
ModelSG_B00CI2KP9O_US
Dimensions & fit
Size1 fl oz
Other details
Skin TypeAll
Skin ToneAll
Item FormSerum
ScentAloe
Key Ingredientsascorbic acid,glycolic acid,licorice,salicylic acid
BenefitsExfoliating
AddressesUneven Pigment

How it compares

This product against the closest alternatives we track in serums.

ProductAmazon ratingRatingsProductDome score
IsisPharma SG_B00CI2KP9O_US SerumThis product4.5 / 57503.8 / 5
Glow Recipe 2404846 SerumGlow Recipe4.6 / 58,4004.6 / 5
mixsoon 8809732910159 Serummixsoon4.5 / 510,1274.5 / 5
Beauty of Joseon 8809738312728 SerumBeauty of Joseon4.5 / 59,4614.5 / 5
medicube 8809982768524 Serummedicube4.6 / 55,1034.5 / 5
Frequently asked

Questions about the IsisPharma SG_B00CI2KP9O_US

Common buyer questions answered straight from the product spec data - no fluff, no "it depends".

What does the IsisPharma serum target?

Uneven pigment, through an exfoliating blend of glycolic and salicylic acid alongside vitamin C and licorice.

Is this serum scented?

Yes, it is listed with an aloe scent.

Is this serum suitable for sensitive or beginner skin?

The listing does not restrict skin type, but combining two exfoliating acids with vitamin C in one step is stronger than what beginners to acids typically start with.