
Hill's Prescription Diet Gastrointestinal Biome Digestive/Fiber Care Dry Dog Food
- Veterinary Diet
- Veterinary Diet
- Bag
- 1
- Better rated than 94%
- More reviewed than 84%
A veterinary-diet dry dog food aimed at digestive and microbiome support, best used on a vet's recommendation rather than as a general everyday kibble.
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How it ranks among the 50 veterinary diets we track
4.8★ across 1,100 Amazon ratings, Bayesian-smoothed toward the category average.
1,100 Amazon ratings, weighted on a log scale so huge counts don't drown everything.
1,000+ bought on Amazon last month.
Brand identity, imagery, description and spec coverage.
The ProductDome score is separate from the Amazon rating shown above: it combines the Bayesian-smoothed Amazon rating with evidence volume, tracked demand, and data quality across the 50 veterinary diets we track - how the scorecard works · full veterinary diets data report. Confidence: high - strong rating volume and complete data.Last refreshed Aug 4, 2026. Data-computed, not a hands-on test. Compiled by the ProductDome Research Team.
Overview
Hill's Prescription Diet Gastrointestinal Biome is a veterinary dry dog food built around ActivBiome+ technology, sold here as a 27.5 lb chicken-flavor bag for adult dogs with sensitive stomachs.
This is a prescription veterinary diet, meaning it's intended for use under a vet's direction rather than picked up as a general everyday food. Hill's label states it's formulated to help firm loose stool within 24 hours and support the gut microbiome through its prebiotic fiber blend.
- ActivBiome+ technology
- 27.5 lb bag, chicken flavor
- Prebiotic fiber blend
- Veterinary diet for sensitive stomach
Who it's for
Intended for dogs whose vet has recommended a gastrointestinal or microbiome-support diet, not for healthy dogs without a digestive issue. As a prescription formula, check with your vet before switching a dog onto it.
Strengths and trade-offs
Drawn from this product's published specifications.
- Prebiotic fiber blend targets microbiome support
- Large 27.5 lb bag reduces reorder frequency
- Prescription veterinary diet, not a general-purpose food
- Requires vet guidance before switching your dog
Performance notes
The formula's ActivBiome+ approach combines a prebiotic fiber blend with higher omega-3 fatty acid content, aimed at supporting gut microbiome balance alongside the stool-firming effect Hill's lists on the label. Being a dairy-free formula, it also removes one common trigger ingredient for dogs with food sensitivities.
Specifications
| Brand | Hill's |
|---|---|
| Model | 605250 |
| Dimensions & fit | |
| Item Weight | 27.5 pounds |
| Dog Breed Size | Medium |
| Capacity & performance | |
| Age Range Description | Adult |
| Included components | |
| Unit Count | 27.5 pounds |
| Included Components | Dry Dog Food |
| Other details | |
| Animal Food Diet Type | Veterinary Diet |
| Container Type | Bag |
| Number Of Items | 1 |
| Manufacturer | Hill's Pet Nutrition |
| Manufacturer Part Number | 605250 |
| Model Number | 605250 |
| Specific Uses For Product | Sensitive Stomach |
| Occasion | Birthday |
| Target Species | Dog |
| Product Benefits | Helps firm loose stool in 24 hours, reduces recurrence, promotes regularity, supports microbiome health |
| Upc | 052742036175 |
| Customer Reviews | {'ratings_count': '1,145', 'stars': '4.8'} |
| Additional Features | ActivBiome+ technology, high omega-3 fatty acids, prebiotic fiber blend |
| Breed Recommendation | All Breed Sizes |
| Recommended Uses For Product | Managing Sensitive Stomach, Promoting Digestive Health |
| Allergen Information | Dairy Free |
| Item Form | Dry Food |
| Asin | B08DJD778K |
| Special Ingredients | Prebiotic |
| Best Sellers Rank | #2,485 in Pet Supplies (See Top 100 in Pet Supplies) #1 in Veterinary Diet Dog Food #187 in Dry Dog Food |
| Flavor | Chicken |
| Item Type Name | Gastrointestinal Biome Digestive/Fiber Care with Chicken Dry Dog Food |
How it compares
This product against the closest alternatives we track in veterinary diets.
| Product | Amazon rating | Ratings | ProductDome score |
|---|---|---|---|
| Hill's Prescription Diet Gastrointestinal Biome Digestive/Fiber Care Dry Dog FoodThis product | 4.8 / 5 | 1,100 | 4.4 / 5 |
| Pro Plan Veterinary Diets Purina UR Urinary Ox/St Canine Formula Dog Food Dry KibblePro Plan Veterinary Diets | 4.6 / 5 | 453 | 4.1 / 5 |
| Royal Canin Veterinary Diet Canine Hepatic Adult Dry Dog FoodROYAL | 4.7 / 5 | 538 | 4.1 / 5 |
| Purina Pro Plan Veterinary Diets HA Hydrolyzed Protein Dog Food Dry Vegetarian FormulaPurina | 4.4 / 5 | 221 | 4.0 / 5 |
| Blue Buffalo Natural Veterinary Diet W+U Weight Management + Urinary Care Dry Dog FoodBlue | 4.6 / 5 | 179 | 3.9 / 5 |
Questions about the Hill's 605250
Common buyer questions answered straight from the product spec data - no fluff, no "it depends".
Is Hill's Prescription Diet GI Biome available without a vet's recommendation?
It's labeled as a prescription veterinary diet, so it's intended to be used on a vet's guidance.
What flavor is this Hill's GI Biome bag?
Chicken.
What size bag does this come in?
27.5 lb.







