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Douxo

Douxo S3 SEB Seboregulating Dog Shampoo 16.9 oz

  • 16.9 fluid ounces, the large bottle
  • 0.5% ophytrium, seboregulating formula
  • Seborrhea, dandruff, odor and oily skin
  • Paraben, phthalate and sulfate free
  • Dogs and cats, hypoallergenic

Last refreshed Aug 4, 2026 · Based on the Amazon listing and published specifications, not hands-on testing.

Our verdict

The large bottle of a seboregulating shampoo for oily, flaky and smelly coats on dogs and cats. It is for ongoing seborrhea care, not a flea or infection treatment.

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ASIN: B09478VXZPModel: S3 SEBCategory: Dog Shampoos

Overview

A grooming room with a large dog or several pets is where this bigger bottle of Douxo S3 SEB makes sense. The seboregulating formula carries ophytrium and targets dandruff, odor and oily or flaky skin.

Free of parabens, phthalates and sulfates, it is meant for repeated use on skin that overproduces oil. The larger bottle suits big dogs or multi-pet homes. Directions for dilution and frequency are not given.

Who it's for

People who bathe oily-coated pets often enough to use up a large bottle. A groomer or multi-pet home gets the most out of the size. A pet with a suspected skin infection needs a medicated product from a vet.

Pros and cons

Pros
  • Large bottle for big dogs
  • Targets seborrhea and flakes
  • Paraben, phthalate and sulfate free
  • Works on dogs and cats
Cons
  • Not a flea treatment
  • Not an antibacterial wash
  • Bathing frequency not listed
  • Bulky to store

Performance notes

The formula pulls excess oil and flakes away during a full lather, so coverage down to the skin sets how well it works. Repeated baths build up the effect on greasy coats. Rinse time and dilution are not listed.

Specifications

BrandDouxo
ModelS3 SEB
Capacity & performance
Liquid Volume16.9 fluid ounceshigher than 77% of 104 dog shampoos
Construction & materials
Material Type FreeParaben, phthalate, sulfate
Included components
Included ComponentsShampoo
Unit Count1 Count
Other details
Product BenefitsSeborrhea
Item FormLiquid
Target SpeciesDog, cat
Scent NameFresh, sweet
Allergen InformationHypoallergenic
Recommended Uses For ProductIrritated skin
Special IngredientsOphytrium 0.5%

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Frequently asked questions

Is Douxo S3 SEB a flea or antibacterial shampoo?

No. The listing covers seborrhea, dandruff, odor and oily or flaky skin, with no flea or infection claim.

Can cats be washed with it?

Yes. The title and target species list dogs and cats.

Is this bottle different from the small one?

The formula is the same as the listed 0.5% ophytrium shampoo, and this is the 16.9 fluid ounce size.

Does it contain sulfates?

No. It is paraben, phthalate and sulfate free.