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Paw

Paw Science Anti-Itch Hydrocortisone Moisturizing Lotion for Dogs & Cats

  • Skin Supplement
  • 1
  • White
  • 4.6 ounces
4.3/ 5 on Amazon287Amazon ratings1,000+bought last month4.0ProductDome score
Medium confidenceLast refreshed Aug 4, 2026Amazon data + ProductDome analysis · methodology
Best forYou are treating a localized hot spot or itchy area on a dog or cat with a topical product.

A hydrocortisone based topical lotion for hot spots and itchy skin on dogs and cats, sold in a 4 oz bottle.

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ProductDome scorecard

How it ranks among the 71 skin supplements we track

4.0/ 5ProductDome scoreMedium confidence
Owner satisfaction · 56% of scorecategory median 4.3★4.3

4.3★ across 287 Amazon ratings, Bayesian-smoothed toward the category average.

Evidence strength · 17% of scorecategory median 956 ratings3.1

287 Amazon ratings, weighted on a log scale so huge counts don't drown everything.

Buyer demand · 11% of score4.1

1,000+ bought on Amazon last month.

Data quality · 11% of score3.8

Brand identity, imagery, description and spec coverage.

The ProductDome score is separate from the Amazon rating shown above: it combines the Bayesian-smoothed Amazon rating with evidence volume, tracked demand, and data quality across the 71 skin supplements we track - how the scorecard works · full skin supplements data report. Confidence: medium - useful but incomplete evidence.Last refreshed Aug 4, 2026. Data-computed, not a hands-on test. Compiled by the ProductDome Research Team.

Overview

This is a hydrocortisone based anti-itch lotion from Paw Science for dogs and cats, sold as a 4 oz sea kelp formula (model PS-HLDC-SK4) aimed at hot spots, itchy skin and minor irritation.

Despite being filed under skin supplements, this is a topical medicated lotion rather than an oral supplement, built around hydrocortisone as the active ingredient. Sea kelp is named in the model title, though the listing does not break out a full ingredient list beyond that.

  • 4 oz bottle, model PS-HLDC-SK4
  • Hydrocortisone based formula
  • Sea kelp named in product title
  • For dogs and cats

Who it's for

Well suited to owners treating a localized hot spot or itchy patch on a dog or cat who want a topical option rather than an oral supplement. Not a substitute for veterinary care if the irritation is widespread or does not improve, since no dosing or duration guidance is included in this listing.

Strengths and trade-offs

Drawn from this product's published specifications.

What stands out
  • Hydrocortisone active ingredient targets itch directly
  • Topical application for localized hot spots
  • Formulated for both dogs and cats
What to check first
  • No full ingredient list beyond sea kelp in the model name
  • No dosing or duration guidance included in this listing

Performance notes

Hydrocortisone is the active mechanism behind the anti-itch effect, applied directly to the affected area rather than taken orally. As a moisturizing lotion it is also meant to soothe dry or irritated skin around a hot spot, not just numb the itch.

Specifications

BrandPaw
ModelPS-HLDC-SK4
Dimensions & fit
Item Weight4.6 ounces
Item Package Dimensions L X W X H5.2 × 1.6 × 1.5 inches
Construction & materials
ColorWhite
Included components
Included Components1x Paw Science Hydrocortisone Lotion for Dogs and Cats - Sea Kelp [4 oz]
Other details
Number Of Items1
Item Model NumberPS-HLDC-SK4
ManufacturerPaw Science
Customer Reviews{'ratings_count': '287', 'stars': '4.3'}
Specific Uses For ProductAnti-Itch, Dog Itching Skin Relief, Dog Rash Treatment, Hot Spot Treatment
Date First AvailableDecember 17, 2025
Model NamePaw Science Hydrocortisone Lotion for Dogs and Cats - Sea Kelp [4 oz]
Target Audience KeywordDogs
AsinB0FM85CLTK

How it compares

This product against the closest alternatives we track in skin supplements.

ProductAmazon ratingRatingsProductDome score
Paw Science Anti-Itch Hydrocortisone Moisturizing Lotion for Dogs & CatsThis product4.3 / 52874.0 / 5
Veterinary Formula Clinical Care Antiseptic and Antifungal Medicated Spray for Dogs & CatsVeterinary4.5 / 527,8054.5 / 5
Pet MD Hydrocortisone Spray for DogsPET4.3 / 516,2184.4 / 5
Zymox Veterinarian Strength Topical Cream with 1% Hydrocortisone for Dogs and CatsZYMOX4.5 / 54,4434.4 / 5
Vetericyn Plus Hot Spot Spray for Dogs Skin Sores and IrritationsVetericyn4.4 / 53,8464.4 / 5
Frequently asked

Questions about the Paw PS-HLDC-SK4

Common buyer questions answered straight from the product spec data - no fluff, no "it depends".

Is this an oral supplement or a topical treatment?

It is a topical lotion applied to the skin, not an oral supplement, despite the skin supplements category label.

What is the active ingredient?

Hydrocortisone, per the product name and title.

Can it be used on both dogs and cats?

Yes, the listing markets it for both dogs and cats.