Differin Adapalene Prescription Strength Retinoid Gel 0.1% Acne Treatment
- Gel
- All
- 1.6 ounces
- Fragrance Free
- More reviewed than 87%
A standard 0.1% adapalene gel sized for months of regular use, useful for acne prevention over time rather than as a fast fix for an active breakout.
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How it ranks among the 238 gels we track
4.6★ across 4,000 Amazon ratings, Bayesian-smoothed toward the category average.
4,000 Amazon ratings, weighted on a log scale so huge counts don't drown everything.
Modest tracked demand last month.
Brand identity, imagery, description and spec coverage.
The ProductDome score is separate from the Amazon rating shown above: it combines the Bayesian-smoothed Amazon rating with evidence volume, tracked demand, and data quality across the 238 gels we track - how the scorecard works · full gels data report. Confidence: high - strong rating volume and complete data.Last refreshed Aug 4, 2026. Data-computed, not a hands-on test. Compiled by the ProductDome Research Team.
Overview
Differin's adapalene gel is a 0.1% retinoid formulated for acne, sold in a 45 gram (1.6 ounce) size described as up to a 90 day supply. It is fragrance free and labeled for all skin types on the face.
Adapalene is a retinoid available over the counter at 0.1% strength, generally used to prevent new acne from forming rather than to treat existing breakouts overnight, and it is applied in thin layers on the whole face rather than spot treated. Retinoids commonly cause dryness or peeling when a routine starts, which is not addressed in the listing itself.
- 0.1% adapalene gel
- 45 gram, up to 90 day supply
- Fragrance free
- Formulated for the face
Who it's for
Fits buyers looking for an over the counter retinoid for ongoing acne prevention on the face. Not intended for spot treatment of a single blemish, and not a fit for anyone new to retinoids without knowing the typical adjustment period.
Strengths and trade-offs
Drawn from this product's published specifications.
- 0.1% adapalene, an established acne preventing retinoid
- Sized for up to a 90 day supply
- Preventive, not a fast fix for active breakouts
- Retinoids commonly require an adjustment period the listing does not cover
Performance notes
At 0.1% adapalene, this sits at the standard over the counter strength, applied as a thin layer across the face rather than spot treated on individual blemishes. The 45 gram size is described as up to a 90 day supply, which frames it for a several month routine rather than short term use.
Specifications
| Brand | Differin |
|---|---|
| Model | 302994910458 |
| Dimensions & fit | |
| Item Weight | 1.6 ounces |
| Package Size Name | 90 Day Supply |
| Construction & materials | |
| Material Features | Fragrance Free |
| Included components | |
| Unit Count | 1.6 ounces |
| Other details | |
| Skin Type | All |
| Asin | B01M114813 |
| Special Ingredients | Adapalene |
| Customer Reviews | {'ratings_count': '4,012', 'stars': '4.6'} |
| Best Sellers Rank | #80,794 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #175 in Facial Cleansing Gels #2,835 in Facial Treatments & Masks |
| Item Form | Gel |
| Upc | 302994910458 |
| Manufacturer | Galderma Laboratories, Inc |
| Scent Name | Unscented |
| Product Benefits | Acne Preventing |
| Manufacturer Part Number | 302994910458 |
| Target Use Body Part | Face |
Other Differin gels
How it compares
This product against the closest alternatives we track in gels.
| Product | Amazon rating | Ratings | ProductDome score |
|---|---|---|---|
| Differin Adapalene Prescription Strength Retinoid Gel 0.1% Acne TreatmentThis product | 4.6 / 5 | 4,000 | 4.0 / 5 |
| Simple Kind to Skin Refreshing Facial Wash GelBrand | 4.6 / 5 | 28,500 | 4.6 / 5 |
| patanjali Aloe Vera Gelpatanjali | 4.4 / 5 | 7,300 | 4.5 / 5 |
| Bioderma Sensibio Foaming Gel Gentle Face CleanserBioderma | 4.7 / 5 | 22,700 | 4.3 / 5 |
| Nature Republic Mild & Moisture Aloe Vera Watery GelNature Republic | 4.6 / 5 | 13,200 | 4.1 / 5 |
Similar gels from other brands
Questions about the Differin 302994910458
Common buyer questions answered straight from the product spec data - no fluff, no "it depends".
What is the adapalene concentration in Differin gel?
0.1 percent.
How long does the 45 gram Differin gel last?
It is listed as up to a 90 day supply.
Is Differin adapalene gel fragrance free?
Yes, it is labeled fragrance free.