
Differin Adapalene Gel 0.1% Acne Treatment
- Gel
- Acne Prone
- 1 ounce
- 2
A dermatologist-grade adapalene gel at drugstore pricing, useful if you already know retinoids work for your skin and want two tubes on hand.
As an Amazon Associate, ProductDome may earn a commission from qualifying purchases made through links on this page.
How it ranks among the 238 gels we track
4.5★ across 454 Amazon ratings, Bayesian-smoothed toward the category average.
454 Amazon ratings, weighted on a log scale so huge counts don't drown everything.
Modest tracked demand last month.
Brand identity, imagery, description and spec coverage.
The ProductDome score is separate from the Amazon rating shown above: it combines the Bayesian-smoothed Amazon rating with evidence volume, tracked demand, and data quality across the 238 gels we track - how the scorecard works · full gels data report. Confidence: high - strong rating volume and complete data.Last refreshed Aug 4, 2026. Data-computed, not a hands-on test. Compiled by the ProductDome Research Team.
Overview
An OTC adapalene 0.1% gel for acne, sold as two 0.5 oz tubes from Galderma. Unscented and formulated for acne-prone skin, it's meant as a nightly retinoid step rather than a spot treatment.
Adapalene is a first-generation retinoid that normalizes skin cell turnover to keep pores clear, and it works on a weeks-not-days timeline. The value pack of two tubes covers a longer stretch of that routine without a second purchase.
- 0.1% adapalene gel
- Two 0.5 oz tubes
- Unscented tube format
- Anti-inflammatory acne treatment
Who it's for
Suited to people with mild to moderate acne who are ready to commit to a retinoid routine. Not a fit for anyone wanting a fast fix or who hasn't tried a retinoid before.
Strengths and trade-offs
Drawn from this product's published specifications.
- Two tubes cover months of nightly use
- Unscented, plain formula for acne-prone skin
- Dermatologist-grade retinoid at accessible pricing
- Retinoids commonly cause initial dryness or peeling
- Results take weeks, not days
- No fragrance-free claim listed despite being unscented
Performance notes
Adapalene works by speeding skin cell turnover so pores stay clearer, with anti-inflammatory benefits built into the formula. Most users see initial dryness or peeling before results show over several weeks of nightly use.
Specifications
| Brand | Differin |
|---|---|
| Model | 302994920303-2a |
| Dimensions & fit | |
| Item Weight | 2.6 ounces |
| Net Content Weight | 0.5 ounces |
| Capacity & performance | |
| Age Range Description | Adult |
| Construction & materials | |
| Material Features | Natural |
| Included components | |
| Unit Count | 1 ounce |
| Package Quantity | 2 |
| Package Type Name | Tube |
| Other details | |
| Skin Type | Acne Prone |
| Number Of Items | 2 |
| Asin | B07N619Q2M |
| Customer Reviews | {'ratings_count': '454', 'stars': '4.5'} |
| Recommended Uses For Product | Anti Inflammatory |
| Best Sellers Rank | #182,179 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #382 in Facial Cleansing Gels |
| Model Number | 302994920303-2a |
| Item Form | Gel |
| Upc | 302990240603 |
| Manufacturer | Galderma |
| Scent Name | Unscented |
| Manufacturer Part Number | 302994920303-2a |
How it compares
This product against the closest alternatives we track in gels.
| Product | Amazon rating | Ratings | ProductDome score |
|---|---|---|---|
| Differin Adapalene Gel 0.1% Acne TreatmentThis product | 4.5 / 5 | 454 | 3.7 / 5 |
| Simple Kind to Skin Refreshing Facial Wash GelBrand | 4.6 / 5 | 28,500 | 4.6 / 5 |
| patanjali Aloe Vera Gelpatanjali | 4.4 / 5 | 7,300 | 4.5 / 5 |
| Bioderma Sensibio Foaming Gel Gentle Face CleanserBioderma | 4.7 / 5 | 22,700 | 4.3 / 5 |
| Nature Republic Mild & Moisture Aloe Vera Watery GelNature Republic | 4.6 / 5 | 13,200 | 4.1 / 5 |
Questions about the Differin 302994920303-2a
Common buyer questions answered straight from the product spec data - no fluff, no "it depends".
What is the active ingredient in Differin Adapalene Gel?
Adapalene 0.1%, a retinoid that normalizes skin cell turnover to help treat acne.
How many tubes come in this pack?
Two 0.5 ounce tubes, combining for 1 ounce total.
Is this gel scented?
No, it's listed as unscented.






