US
PanOxyl

PanOxyl Adapalene 0.1% Leave-On Gel

  • Gel
  • 1
  • Oil Free
  • 0.5 ounces
4.6/ 5 on Amazon2,100Amazon ratings3.9ProductDome score
  • More reviewed than 78%
High confidenceLast refreshed Aug 4, 2026Amazon data + ProductDome analysis · methodology
Best forYou want an over-the-counter adapalene retinoid gel for ongoing acne management.

A standard-strength adapalene gel for acne-prone skin, comparable in active ingredient to other 0.1% adapalene products on the market.

View current price on Amazon →

As an Amazon Associate, ProductDome may earn a commission from qualifying purchases made through links on this page.

ProductDome scorecard

How it ranks among the 238 gels we track

3.9/ 5ProductDome scoreHigh confidence
Owner satisfaction · 56% of scorecategory median 4.6★4.6

4.6★ across 2,100 Amazon ratings, Bayesian-smoothed toward the category average.

Evidence strength · 17% of scorecategory median 461 ratings4.2

2,100 Amazon ratings, weighted on a log scale so huge counts don't drown everything.

Buyer demand · 11% of score0.0

Modest tracked demand last month.

Data quality · 11% of score3.8

Brand identity, imagery, description and spec coverage.

The ProductDome score is separate from the Amazon rating shown above: it combines the Bayesian-smoothed Amazon rating with evidence volume, tracked demand, and data quality across the 238 gels we track - how the scorecard works · full gels data report. Confidence: high - strong rating volume and complete data.Last refreshed Aug 4, 2026. Data-computed, not a hands-on test. Compiled by the ProductDome Research Team.

Overview

A leave-on retinoid gel from PanOxyl formulated with adapalene USP 0.1%, made by Crown Laboratories for acne-prone skin. It ships as a 0.5 oz, 30-day supply and is free of oil, fragrance and parabens.

Adapalene 0.1% is the active ingredient behind the well-known Differin gel, an FDA-approved topical retinoid available over the counter for acne. PanOxyl's version packages the same active at the same strength, positioned by the brand to help stop breakouts from forming rather than treat existing ones after the fact.

  • 0.5 oz adapalene 0.1% leave-on gel
  • 30-day supply
  • Made by Crown Laboratories
  • Oil, fragrance and paraben free

Who it's for

Aimed at adults dealing with ongoing acne who want an over-the-counter retinoid gel rather than a spot treatment. Not intended for children, and anyone new to retinoids should expect an adjustment period of dryness or peeling.

Strengths and trade-offs

Drawn from this product's published specifications.

What stands out
  • Contains adapalene USP 0.1%, the same active as leading over-the-counter retinoid gels
  • Oil, fragrance and paraben free
  • 30-day supply sized for a full initial course
What to check first
  • Retinoids commonly cause initial dryness or peeling as skin adjusts
  • Results take weeks of consistent use, not immediate
  • No customer review data available

Performance notes

Topical adapalene works by normalizing skin cell turnover to keep pores from clogging, so it is applied nightly as a preventive step and typically takes several weeks of consistent use before breakouts noticeably reduce. Initial dryness, redness or peeling is common as skin adjusts.

Specifications

BrandPanOxyl
ModelPXL14315
Dimensions & fit
Net Content Weight0.5 ounces
Item Dimensions6.4 × 2.9 × 1.3 inches
Capacity & performance
Age Range DescriptionAdult
Construction & materials
Material Type FreeOil Free
Included components
Package Type NameBottle
Other details
Number Of Items1
AsinB0C11DJ94K
Special Ingredientspanoxyl
Customer Reviews{'ratings_count': '2,110', 'stars': '4.6'}
Model NumberPXL14315
Target AudienceWomen
Item FormGel
Upc303160143151 303160284151
Active IngredientsAdapalene USP 0.1%
ManufacturerCrown Laboratories
Product BenefitsStops breakouts from forming
Manufacturer Part NumberPXL14315
Global Trade Identification Number00303160143151

How it compares

This product against the closest alternatives we track in gels.

ProductAmazon ratingRatingsProductDome score
PanOxyl Adapalene 0.1% Leave-On GelThis product4.6 / 52,1003.9 / 5
Simple Kind to Skin Refreshing Facial Wash GelBrand4.6 / 528,5004.6 / 5
patanjali Aloe Vera Gelpatanjali4.4 / 57,3004.5 / 5
Differin Acne Treatment GelDifferin4.5 / 571,0004.3 / 5
Bioderma Sensibio Foaming Gel Gentle Face CleanserBioderma4.7 / 522,7004.3 / 5
Frequently asked

Questions about the PanOxyl PXL14315

Common buyer questions answered straight from the product spec data - no fluff, no "it depends".

What is the active ingredient in PanOxyl's adapalene gel?

Adapalene USP 0.1%, an over-the-counter topical retinoid.

How long does the 0.5 oz tube last?

It is sized as a 30-day supply.

Is this gel fragrance free?

Yes, it is listed as oil, fragrance and paraben free.